A) Proportion of patients according to the number of risk factors. B) Progression-free survival (PFS) according to the number of risk factors; PFS of patients with two versus three, and three versus four risk factors was not statistically significantly different, and hence, these groups were combined in the high-risk category. C) PFS according to Burkitt lymphoma International Prognostic Index (BL-IPI) risk group. D) Overall survival (OS) according to BL-IPI risk group; 3-year PFS and OS estimates are listed with 95% CIs (in parentheses); p values are from log-rank tests comparing groups sequentially and from an overall log-rank test. Abbreviations: LDH, lactate dehydrogenase; ULN, upper limit of normal. From J Clin Oncol, Olszewski AJ, Jakobsen LH, Collins GP, et al, Burkitt Lymphoma International Prognostic Index, vol. 39, pp 1129-1138, Copyright © 2021 Wolters Kluwer Health, Inc. Reprinted with permission from Wolters Kluwer Health, Inc.