Survival probabilities for the DIPSS risk groups in MF receiving HCT vs non-HCT therapy. (A) DIPSS low risk. (B) DIPSS Int-1. (C) DIPSS Int-2 or higher. (D) Overall (all DIPSS groups). The survival curves presented here, stratified by DIPSS risk score, are a representation of the interventions (ie, HCT vs non-HCT therapy) over a median follow-up of ∼6 years. The curves cross much later in the clinical course than 12 months; however, the slope of the curves changes much earlier (12 months) and then plateaus, indicating the OS benefit associated with HCT begins much earlier than when the curves actually cross. A long-term survival advantage with HCT was observed for patients with Int-1 or higher risk MF, but at the cost of early mortality. The magnitude of OS benefit increased as DIPSS risk score increased.