Survival of RS-PDX IV models treated with Duv, Ven, and their combination. Survival curves of (A) RS1316 and (B) RS9737 systemic RS-PDX models treated with vehicle (Veh; blue), Duv (red), Ven (green), and their combination (Duv/Ven; gray). En, engraftment; Tx, treatment. Statistical analysis was performed using Mantel-Cox test; *P < .05, **P < .01, ***P < .001, ****P < .0001.