Tumor growth kinetics of RS-PDX SC models treated with Duv, Ven, and their combination. (A) Tumor volume at the end of treatments in the 4 RS-PDX SC models. Data are reported as mean ± SEM. (B) Tumor growth kinetic of RS-PDX SC models treated with vehicle (Veh; blue), Duv (red), Ven (green), and their combination (Duv/Ven; gray). Data are reported as mean ± SEM. Tx, treatment; W/W, watch and wait. Statistical analysis was performed using 1-way ANOVA (A) and a multiple Student t test (B); *P < .05, **P < .01, ***P < .001, ****P < .0001.