Comparison of comutational profiles for all patients with de novo AML with mutated DNMT3A. All cases of de novo AML with mutated DNMT3A evaluated (n = 104). Each column represents an individual patient. Intensity gradient corresponds to DNMT3A VAF. All comutations are provided in binary format with a black box indicating presence of comutation in that patient. The number and percentage of cases with a specific comutation are listed on the left (for DNMT3A^LOW cases) and right (for DNMT3A^HIGH cases).