OCT1, OCT2, and OBF1 occupy active functional genomic elements. (A) Genomic distribution of OBF1/OCT1/OCT2 peaks under LPS stimulation. “Promoters” are defined as TSS ± 1 kb. “Downstream” is defined as within 3 kb downstream of 3′ untranslated region. (B) Distributions of distances among OBF1, OCT1, OCT2, and H3K27ac peaks and the nearest TSS (log₁₀ scale). (C) OBF1, OCT1, OCT2, and H3K27ac ChIP-seq enrichments in 10-kb genomic windows centered on the middle of overlapping peaks among OBF1, OCT1, and OCT2. ChIP-seq was performed with CD19⁺ splenic B cells treated with LPS for 72 hours. (D) OCT1, OBF1, OCT2, H3K27ac, H3K4me1, and H3K4me3 ChIP-seq read densities at 2 individual gene loci, illustrating the colocalization of measured signals.