Figure 4.
Characteristics of the patients with IDH2R172-mutated AML. (A) Volcano plot representing the association between IDH2R172 variants and covariates (estimate of the point-biserial correlation [continuous variables] or Φ [dichotomous variables] on the x-axis) and the significance of the difference, expressed on an inverted logarithmic scale on the y-axis. The P value was calculated using the Mann-Whitney U test (continuous variables) or Fisher’s exact (dichotomous) test. The size of the circle corresponds to the frequency of the variable in the cohort. Only covariates with q < 0.05 are highlighted. (B) OS censored at HSCT in patients with IDH2R172 mutations, according to the platelet counts at diagnosis (arbitrary cutoff at 100 × 109/L).

Characteristics of the patients with IDH2R172-mutated AML. (A) Volcano plot representing the association between IDH2R172 variants and covariates (estimate of the point-biserial correlation [continuous variables] or Φ [dichotomous variables] on the x-axis) and the significance of the difference, expressed on an inverted logarithmic scale on the y-axis. The P value was calculated using the Mann-Whitney U test (continuous variables) or Fisher’s exact (dichotomous) test. The size of the circle corresponds to the frequency of the variable in the cohort. Only covariates with q < 0.05 are highlighted. (B) OS censored at HSCT in patients with IDH2R172 mutations, according to the platelet counts at diagnosis (arbitrary cutoff at 100 × 109/L).

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