Characteristics of patients with IDH2R140-mutated AML. (A) Volcano plot representing the association between IDH2R140 variants and covariates (estimate of the point-biserial correlation [continuous variables] or Φ [dichotomous variables] on the x-axis) and the significance of the difference. The P value was calculated using a Mann-Whitney (continuous variables) U test or Fisher’s exact (dichotomous) test, expressed on an inverted logarithmic scale on the y-axis. The size of the circle corresponds to the frequency of the variable in the cohort. Only covariates with q < 0.05 are highlighted. (B) OS censored at HSCT in IDH2R140-mutated patients according to the karyotype and NPM1 mutational status. (C) DFS censored at HSCT according to the mutational statuses of NPM1 and DNMT3A.