Outcome of the 358 patients in the FL2000 study with a 5-year median follow-up. (A) Event-free survival. (B) Response duration from the end of treatment (for 258 of 273 responding patients with a confirmed date of response evaluation). (C) Overall survival. Arm A (CHVP+I): blue solid line; Arm B (R-CHVP+I): dotted red line.