Prognostic value and expression of G9a and GLP in MM. (A) The expression profile of G9a and GLP was investigated in the MMRF cohort (n = 674). (B-D) The prognostic value of G9a in terms of OS was determined in newly diagnosed MM patients using the MMRF cohort (B; n = 674) and the Montpellier cohort (C; n = 68), as well as in relapsed MM patients from the Mulligan cohort (D; n = 188). Maxstat analysis was used to calculate the optimal separation of patients based on a cutoff value.