Individual-level analysis for the EORTC QLQ-C30 scales included in the primary analysis. Global health status/QoL (A), physical functioning (B), fatigue (C), and pain (D). Data are for the EORTC QLQ-C30–evaluable population. Percentages were calculated using the total number of patients who had provided answers for ≥50% of the items on the given scale. Improvement was defined as a ≥10-point increase from baseline (global health status/QoL and physical functioning) or ≥10-point decrease from baseline (fatigue and pain). No change was defined as a <10-point increase or decrease from baseline. Deterioration was defined as a ≥10-point decrease from baseline (global health status/QoL and physical functioning) or ≥10-point increase from baseline (fatigue and pain).