Changes in EORTC QLQ-C30 scores over time for the scales included in the primary analysis. Global health status/QoL (A), physical functioning (B), fatigue (C), and pain (D). Data are for the EORTC QLQ-C30–evaluable population. The MID was defined as a ≥10-point change in either direction. *Unadjusted P value for change from baseline <.05, 2-sided Wilcoxon signed-rank test. The test was performed only for assessments where the sample size was ≥10. SE, standard error.