Comorbid profile of clonal hematopoiesis in highly aged individuals. Forest plot showing odds ratios for the association between the presence of CH and prevalent age-related comorbidities, derived from univariable logistic regression. Circles indicate the odds ratio, with horizontal lines corresponding to the 95% CI. Polypharmacy was defined as ≥5 medications. Obesity was defined as body mass index ≥30 kg/m². MI, myocardial infarction; MMSE, Mini-Mental State Examination; N, number of individuals with respective medical history and total number of evaluable individuals; TIA, transient ischemic attack.