Figure 4.
Five-year cumulative incidence of relapse.KMT2D mutational status (A), KMT2D and PTEN mutational status (B), KMT2D and PTEN mutational status on an N/Fwt background (C) and KMT2D and PTEN mutational status on an N/Fmut background (D). A VAF cutoff of >10% and only nonsynonymous mutations were included for analysis. In case of N/Fmut, only mutations from the hotspots (exons 26, 27, and 34 for NOTCH1 and exons 9, 10, and 12 for FBXW7) were included.

Five-year cumulative incidence of relapse.KMT2D mutational status (A), KMT2D and PTEN mutational status (B), KMT2D and PTEN mutational status on an N/Fwt background (C) and KMT2D and PTEN mutational status on an N/Fmut background (D). A VAF cutoff of >10% and only nonsynonymous mutations were included for analysis. In case of N/Fmut, only mutations from the hotspots (exons 26, 27, and 34 for NOTCH1 and exons 9, 10, and 12 for FBXW7) were included.

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