Schematic display of localization and frequencies of mutations in KMT2D and prognostic value of the most relevant candidate genes. Schematic display of localization and frequencies of mutations identified for KMT2D in total T-LBL samples (VAF cutoff, >1%) (A), KMT2D in relapse⁺ samples (B). The data for mutations (A-B) in pediatric patients with T-ALL were imported from the St Jude Pediatric Cancer Genomic data portal and are displayed in the lower part of the schematic structure, and the mutations identified in the current T-LBL project are displayed in the upper part.