ox-mtDNA levels correlate with known biomarkers of inflammasome activation. Log₁₀-transformed, glucose-adjusted ox-mtDNA is correlated with known MDS inflammasome activating alarmins in S100A8 and S100A9 (A) and ASC (B) specks in patient PB plasma. (C) ROC/AUC analyses of ox-mtDNA and ASC speck percentage in MDS patients vs controls.