Box plots representing the clonality of all sample categories based on the distinct clonotypes identified per sample. Statistical analysis of the clonality patterns revealed that the IGLV-IGLJ gene rearrangements of subset 2 were significantly (P < .05) more diverse than those in all other data sets, whereas those of subset 169 and the nonsubset IGLV3-21 cases did not differ from each other and could form a homogeneous group. The IGHV-IGHD-IGHJ gene rearrangements of subsets 2 and 169 did not differ from each other either, but significantly differed from all LC categories (P < .05). For detailed results of the statistical analysis see supplemental Table 7. HC, heavy chain; LC, light chain.