DDAVP challenge test response. Graph showing the fold change in VWF:Act vs baseline at 1 to 1.5 hours and 3 to 4 hours post-DDAVP in the study population. The boxes show the median values (dashed lines) at those time points (2.91 and 2.05, respectively). The box extends from the 25th percentile to the 75th percentile. The whiskers extend from the minimum and maximum observed values which are within 1.5 times the IQR. The solid black diamond represents the mean value. The colored lines with dashed and solid patterns represent results from various patients.