A timeline of the history of immunotherapy. Although based on old medical practices such as variolation, the progresses of immunotherapy methods have strongly accelerated in the recent years with multiple discoveries concerning mostly antibodies (in blue), antigens and cellular immunity (in orange), and more recently genome edition (in red). Although this figure mentions important milestones and notably Nobel Prizes, all these progresses have clearly resulted from the joint and incremental efforts of multiple scientists and medical teams throughout the world.