Figure 5.
Impaired mobilization in chimeric mice with FGF-23−/− BM. (A) Efficiency of G-CSF mobilization as assessed by WBCs, LSKs, and CFU-Cs in the blood in wild-type mice that harbor FGF-23+/+ and FGF-23−/− BM (chimeric mice: n = 6 for the PBS/BSA group and n = 12 for the G-CSF group). (B) iFGF-23 protein in BM extracellular fluid of chimeric mice after G-CSF mobilization (n = 6). Combined data of at least 3 independent experiments are shown. Data are means ± SEM. **P < .01; ***P < .001 (Student t test).

Impaired mobilization in chimeric mice with FGF-23−/− BM. (A) Efficiency of G-CSF mobilization as assessed by WBCs, LSKs, and CFU-Cs in the blood in wild-type mice that harbor FGF-23+/+ and FGF-23−/− BM (chimeric mice: n = 6 for the PBS/BSA group and n = 12 for the G-CSF group). (B) iFGF-23 protein in BM extracellular fluid of chimeric mice after G-CSF mobilization (n = 6). Combined data of at least 3 independent experiments are shown. Data are means ± SEM. **P < .01; ***P < .001 (Student t test).

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