Expression of FGF-23 protein in BM. iFGF-23 protein in BM extracellular fluid after single-dose G-CSF (A) at the indicated hours (n = 4) and during G-CSF mobilization (B) (n = 7-8). Inorganic phosphate (C) (IP; n = 5) and iFGF-23 protein (D) (n = 7-8) in the blood in G-CSF mobilization. (E) iFGF-23 and cFGF-23 protein levels in the blood and BM extracellular fluid in mice treated with 6 doses of G-CSF (n = 6). Combined data of at least 3 independent experiments are shown. Data are means ± SEM. *P < .05; **P < .01; ***P < .001 (ANOVA and Student t test).