Total 1-year health care costs of the 10 diagnostic scenarios plotted against the predicted mortality per 10 000 patients. Cost-effectiveness plane and efficient frontier (dashed lines) indicating the possibly cost-effective options among the 10 diagnostic scenarios and a scenario to treat all, treat none, and treat those with a likely clinical probability and/or abnormal D-dimer without diagnostic imaging (depending on willingness to pay to prevent mortality). For strategy numbers, see Figure 1.