One-year health care costs per patient for the 10 diagnostic scenarios. One-year health care costs per patient for the 10 diagnostic scenarios, including a scenario to treat all, treat none, and treat those with a likely clinical probability and/or abnormal D-dimer without diagnostic imaging. CDR+DD, clinical decision rule + D-dimer testing; CUSi, compression ultrasonography is positive, negative, or inconclusive; FN, false negatives; FP, false positives.