Figure 5.
Gene fusions found by CCA, WTS, and LD-RTPCR. Each circle represents a set of gene fusions (in rows, possibly multiple fusions per patient) found by a unique combination of techniques (in columns); the size of the circle is proportional to the event count (also shown inside the circle). The combination of techniques for each column is described at the top of the figure: a plus sign (+) implying that the technique found the fusion, a minus sign (−) implying that it did not report the fusion, and NP denoting that the technique was not performed. Fusions are grouped according to their presence in the ELN classification (red), their relevance in AML according to other publications (orange), or their lack of relation to AML (gray). Perfect matches between the performed techniques are shown in green, whereas fusions found only in WTS with low experimental evidence (few supporting reads) and unknown translocations found only in CCA are further grouped at the bottom of the figure. For each fusion or translocation, the cytogenetic ranges considered are presented in bold type, and the fused genes are shown in italics on the left. For fusions found only by CCA, fused genes could only be inferred according to the locus and are marked by an asterisk (*). Nonrecurring or unknown fused genes are denoted as “...”

Gene fusions found by CCA, WTS, and LD-RTPCR. Each circle represents a set of gene fusions (in rows, possibly multiple fusions per patient) found by a unique combination of techniques (in columns); the size of the circle is proportional to the event count (also shown inside the circle). The combination of techniques for each column is described at the top of the figure: a plus sign (+) implying that the technique found the fusion, a minus sign (−) implying that it did not report the fusion, and NP denoting that the technique was not performed. Fusions are grouped according to their presence in the ELN classification (red), their relevance in AML according to other publications (orange), or their lack of relation to AML (gray). Perfect matches between the performed techniques are shown in green, whereas fusions found only in WTS with low experimental evidence (few supporting reads) and unknown translocations found only in CCA are further grouped at the bottom of the figure. For each fusion or translocation, the cytogenetic ranges considered are presented in bold type, and the fused genes are shown in italics on the left. For fusions found only by CCA, fused genes could only be inferred according to the locus and are marked by an asterisk (*). Nonrecurring or unknown fused genes are denoted as “...”

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