Mutational status of single-cell colonies derived from CD34⁺ 38⁻BM progenitor cells in 7 ECD patients. Mutational status of single-cell colonies derived from CD34⁺38⁻ progenitor cells of 3 ECD patients (#A, B/13, and C) harboring both MAPK pathway and additional myeloid mutations, and of 5 ECD patients (#D/7, E, F/4, G/16, and H) harboring myeloid mutations. Of note, a larger number of colonies were sequenced for the MAPK pathway mutations and only the colonies sequenced for both MAPK pathway mutations and additional myeloid mutations are depicted. Patients who had hematological neoplasms are indicated by “/X”, the X number referring to the number on Table 3. The full details of the mutation list, and correspondence between BM and tissue mutations, are shown in supplemental Table 7.