Proteomic basis of failed NETosis capacity. (A) Overlap in protein differences between circulating GPS and control blood neutrophils (HC PMN) vs MPB CD34⁺ HSC-derived neutrophils and circulating blood-derived neutrophils (HC PMN). (B) Heatmap of 22 overlapping proteins between the same cell groups as shown in panel A. (C) STRING-DB interaction network of 13 proteins with shared reduced abundancy. (D) Dot and line plots of 13 proteins with shared reduced abundancy. Blue dots present LFQ values, and red dots represent median LFQ values.