Frequency of JAK2V17F in the general population and in associated laboratory and clinical phenotypes. Data are from the Danish Suburban Population Survey.³³  (A) JAK2V617F was identified in 3% (615/19958) of the general population, represented as the small chip within the larger oval. The arrow indicates an enlargement of this chip and shows that JAK2V617F MPN comprised only 2.6% of the total JAK2V617F CH population, with JAK2V617F MPN phenotypes indicated as overlapping colored circles. (B) Average blood counts and associated venous thromboembolism (VTE) and ischemic cerebrovascular disease (ICVD) from the non-mutated (CALR-negative and JAK2V617F-negative) and JAK2V617F-positive populations stratified by JAK2V617F VAF). Asterisks indicate significantly different values compared with the nonmutated population (*P < .05). WBC, white blood cell.