In vivo persistence in blood and egress to tissues sites by mRNA EP-transfected granulocyte-rich apheresis product cells. Infusion of apheresis cells into mice. High doses of GFP mRNA-transfected granulocytes (up to 300 × 10⁶ cells per mouse) were IV injected into mice at 24 hours post-EP. GFP expression (B) was followed in the human CD45⁺ cells (A) after 24 hours in the PB and after 72 hours in the PB (n = 3-5 animals), liver, lungs, and spleen (n = 1).