Multivariate analysis of TTP and PFS. (A) Forest plot of multivariate CSH models with probabilities for each factor associated with TTP and PFS of MM based on age, ISS III vs I/II, LDH high level, plasmacytoma, FISH risk (high cytogenetic risk, including del17p, t(4;14) and/or t(14;16), vs standard risk), and the expression level of the studied proteins (n = 125); samples with missing values were removed from the model. (B) Forest plot of multivariate CSH models with probabilities for each factor associated with TTP and PFS of MM based on clinical variables, including age, ISS III vs I/II, LDH high level, plasmacytoma, and FISH risk (high cytogenetic risk, including del17p, t(4;14), and t(14;16) vs standard risk). (C) Contribution of variables to explaining the model adjustment calculated by the relative proportion of χ².