Figure 2.
Flow cytometric analysis of immune checkpoint markers. Expression on T cells (CD3+), cytotoxic T cells (CD3+, CD8+), helper T cells (CD3+, CD4+), Tregs (CD3+, CD4+, CD25+, CD127low/−), and NK cells (CD3−, CD56+) was determined by flow cytometry. PD-1 (A), OX-40 (B), and 4-1BB (C) expression in patients with TP53 mutations vs patients with the wild-type gene. *P ≤ .05, **P ≤ .01, ***P ≤ .001, ****P < .0001.

Flow cytometric analysis of immune checkpoint markers. Expression on T cells (CD3+), cytotoxic T cells (CD3+, CD8+), helper T cells (CD3+, CD4+), Tregs (CD3+, CD4+, CD25+, CD127low/−), and NK cells (CD3−, CD56+) was determined by flow cytometry. PD-1 (A), OX-40 (B), and 4-1BB (C) expression in patients with TP53 mutations vs patients with the wild-type gene. *P ≤ .05, **P ≤ .01, ***P ≤ .001, ****P < .0001.

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