Figure 5.
Prominent circRNAs upregulated with T-ALL group specificity. Expression in CD34+ and in DP developing thymocytes from healthy donors and in samples of different T-ALL groups of 11 circRNAs significantly upregulated in 1 T-ALL group compared with all other T-ALL samples, with CD34+ and with DP thymocytes (***, **, and * indicate differential expression with adjusted P < .001, <.01, and <.05, respectively). The predicted exon structure with the backsplice junction validated by RT-PCR and Sanger sequencing is shown for each circRNA (different colors indicate the group specificity and different color shades exons putatively included in the circRNA; the chromatogram depicts the sequence of the backsplice junction exactly corresponding to that identified by RNA-seq).

Prominent circRNAs upregulated with T-ALL group specificity. Expression in CD34+ and in DP developing thymocytes from healthy donors and in samples of different T-ALL groups of 11 circRNAs significantly upregulated in 1 T-ALL group compared with all other T-ALL samples, with CD34+ and with DP thymocytes (***, **, and * indicate differential expression with adjusted P < .001, <.01, and <.05, respectively). The predicted exon structure with the backsplice junction validated by RT-PCR and Sanger sequencing is shown for each circRNA (different colors indicate the group specificity and different color shades exons putatively included in the circRNA; the chromatogram depicts the sequence of the backsplice junction exactly corresponding to that identified by RNA-seq).

Close Modal

or Create an Account

Close Modal
Close Modal