Gut diversity and associations with aGVHD. Gut microbial diversity in inverse Simpson index (A), gene richness (B), and metabolic richness (C) in those who developed vs those who did not develop aGVHD pre-aHSCT and early post-aHSCT samples. Kruskal-Wallis tests were performed per diversity measure and period. y_min lower whisker is smallest observation greater than or equal to lower hinge − 1.5 * IQR; y_max upper whisker is largest observation less than or equal to upper hinge + 1.5 * IQR.