Various PNH clones with CN-LOH regions of different lengths from II-7 (mother). (A) SNP array analysis of chromosome 15q in PNH-type granulocytes and T cells from II-7 using CytoScan HD Array. There were at least 4 clones with different sizes of CN-LOH in PNH cells, and the sizes and number of CN-LOH clones in granulocytes and T cells were almost the same. As the probes for chromosome 15p were missing in the kit, the exact spanning size of the longest CN-LOH was unknown (shaded areas). (B) Percentage of each clone with different sizes of CN-LOH estimated from the pattern of allele differences.