Pedigree of the family and GPI-AP-deficiency of the patient and her mother. (A) Pedigree. Family members tested are indicated by an asterisk. The patient (III-1) and her mother (II-7) have a PNH clone. The aunt (II-10) has a heterozygous PIGB mutation c.695G>A but no PNH clone. The daughter (IV-1) and uncle (II-11) have no PIGB mutation. (B) Flow cytometry of blood cells from the patient (III-1) and her mother (II-7).