Genetic comparison of t(14;18)⁻FL cases with cFL, PTFL, NMZL, and DTFL. (A) CN comparison of t(14;18)⁻ FL vs PTFL.²⁶  Comparative plot of CN and CNN-LOH between 53 t(14;18)⁻ FL cases and 42 PTFL cases. Significantly different regions are indicated in the plot, and the color denotes the enriched group (Fisher’s exact test; adjusted P < .05; minimum of 3 cases). (B) CN comparison of t(14;18)⁻ FL vs NMZL. Comparative plot of CN and CNN-LOH between 53 cases of t(14;18)⁻ FL and 35 of NMZL. No significant differences were observed between groups (Fisher’s exact test; adjusted P < .05; minimum of 3 cases). Nonetheless, some differences could be detected using raw nonadjusted P values. These differentially affected regions are indicated in the plot, and the color denotes the enriched group (Fisher's exact test; P < .05; minimum of 3 cases).²⁴  (C) Comparison of recurrent mutations of t(14;18)⁻ FL vs cFL, PTFL, NMZL, and DTFL. Frequencies of recurrently mutated genes (>5% cases) in 45 t(14;18)⁻ cases and 22 cFL,⁵  24 PTFL,²⁵  35 NMZL,²⁴  and 31 DTFL.³²  Asterisk color indicates significant differences between t(14;18)⁻ FL and the associated color group (Fisher’s exact test; P < .05).