Sequencing data of both donor and recipient after allogeneic hematopoietic stem cell transplantation at time of diagnosis of DCHN. NGS was performed by using a panel of 21 genes relevant to myeloid malignancies. Shallow whole-genome sequencing (sWGS) was performed only of both donor and recipient samples as described in case 1 (details are provided in the supplemental Data). Definitions of hematologic neoplasms are according to the updated (2016) World Health Organization classification and to Valent et al.³  AML-M2, acute myeloid leukemia with maturation; AML-M5, acute monoblastic leukemia; Dx, diagnosis; CHIP, CH of indeterminate potential; MDS-MLD, MDS with multilineage dysplasia; MDS-RS-MLD, MDS with ring sideroblasts and multilineage dysplasia; yo, years old.