The screening of new ceramide analogs with anti-PEL activities. (A) The chemical structures of our newly synthetic ceramide analogs. (B) KSHV⁺ PEL cell line, BCBL-1, was treated with 20 µM of analogs or vehicle for 48 hours. The cell proliferation status was then examined using the WST-1 Cell Proliferation Assay (Roche). The cell growth inhibitory rates were calculated by comparing to the vehicle-treated controls. Error bars represent standard deviation (SD) for 3 independent experiments.