Distribution of HSPC subpopulations by immunophenotype, percentage, and absolute cell count
| Cell type . | Immunophenotype . | Percentage . | Absolute no. . |
|---|---|---|---|
| HSC | Lin−34+38−45RA−90+ | 6.7 (0.1-17.3) | 5.8 × 104 (3.9 × 102-9.4 × 105) |
| MPP | Lin−34+38−45RA−90− | 10.6 (1.1-37.5) | 7.9 × 104 (1.4 × 103-2.5 × 106) |
| CMP | Lin−34+38+45RA−123+ | 33.6 (3.2-45.8) | 3 × 105 (4.1 × 103-1.9 × 106) |
| GMP | Lin−34+38+45RA+123+ | 20.8 (7.1-51.9) | 1.9 × 105 (1.8 × 103-2 × 106) |
| MEP | Lin−34+38+45RA−123− | 11.4 (3.8-22.9) | 8.9 × 104 (1.4 × 103-6.8 × 105) |
| CLP | Lin−34+38+127+ | 0.0071 (0-0.064) | 5.6 × 101 (0-7.8 × 102) |
| Pro-B/NK | Lin−34+38+45RA+10+ | 1.2 (0.2-4.4) | 1.1 × 104 (1.5 × 102-2 × 105) |
| MLP | Lin−34+38−45RA+10+ | 1.1 (0.3-4.6) | 9 × 103 (4.4 × 102-1.1 × 105) |
| LMPP | Lin−34+38−45RA+90v | 3.3 (0.9-16.5) | 3.1 × 104 (3.9 × 102-1.1 × 106) |
| Cell type . | Immunophenotype . | Percentage . | Absolute no. . |
|---|---|---|---|
| HSC | Lin−34+38−45RA−90+ | 6.7 (0.1-17.3) | 5.8 × 104 (3.9 × 102-9.4 × 105) |
| MPP | Lin−34+38−45RA−90− | 10.6 (1.1-37.5) | 7.9 × 104 (1.4 × 103-2.5 × 106) |
| CMP | Lin−34+38+45RA−123+ | 33.6 (3.2-45.8) | 3 × 105 (4.1 × 103-1.9 × 106) |
| GMP | Lin−34+38+45RA+123+ | 20.8 (7.1-51.9) | 1.9 × 105 (1.8 × 103-2 × 106) |
| MEP | Lin−34+38+45RA−123− | 11.4 (3.8-22.9) | 8.9 × 104 (1.4 × 103-6.8 × 105) |
| CLP | Lin−34+38+127+ | 0.0071 (0-0.064) | 5.6 × 101 (0-7.8 × 102) |
| Pro-B/NK | Lin−34+38+45RA+10+ | 1.2 (0.2-4.4) | 1.1 × 104 (1.5 × 102-2 × 105) |
| MLP | Lin−34+38−45RA+10+ | 1.1 (0.3-4.6) | 9 × 103 (4.4 × 102-1.1 × 105) |
| LMPP | Lin−34+38−45RA+90v | 3.3 (0.9-16.5) | 3.1 × 104 (3.9 × 102-1.1 × 106) |
Data are shown as median (range). Percentages are among live CD34+ cells.
CMP, common myeloid progenitor; GMP, granulocyte/monocyte progenitor; LMPP, lymphoid-primed multipotent progenitor; MEP, megakaryocyte/erythrocyte progenitor; MLP, multipotent lymphoid progenitor; MPP, multipotent progenitor; pro-B/NK, B/natural killer cell progenitor.