Summary of common clinical and pathologic features of HSTCL
| Common HSTCL features . | Patients . |
|---|---|
| Median age (range), y | 34 (5-68) |
| Previous solid organ transplant, % | 0-19 |
| Immune compromise, % | 2-27 |
| Elevated LDH, % | 55-62 |
| Abnormal LFT, % | 38-43 |
| Anemia, % | 73-84 |
| Thrombocytopenia, % | 45-95 |
| Neutropenia, % | 36-85 |
| Splenomegaly, % | 97-100 |
| Hepatomegaly, % | 40-80 |
| Adenopathy, % | 0-13 |
| Isochrome 7q, % | 25-70 |
| Trisomy 8, % | 8-53 |
| Immunophenotype | CD2+, CD3+, CD4−, CD5−, CD7+, CD8−, γδ TCR+, TIA1+ |
| Common HSTCL features . | Patients . |
|---|---|
| Median age (range), y | 34 (5-68) |
| Previous solid organ transplant, % | 0-19 |
| Immune compromise, % | 2-27 |
| Elevated LDH, % | 55-62 |
| Abnormal LFT, % | 38-43 |
| Anemia, % | 73-84 |
| Thrombocytopenia, % | 45-95 |
| Neutropenia, % | 36-85 |
| Splenomegaly, % | 97-100 |
| Hepatomegaly, % | 40-80 |
| Adenopathy, % | 0-13 |
| Isochrome 7q, % | 25-70 |
| Trisomy 8, % | 8-53 |
| Immunophenotype | CD2+, CD3+, CD4−, CD5−, CD7+, CD8−, γδ TCR+, TIA1+ |
Summary of clinical and pathologic characteristics based on largest series.17,19-21
LFT, liver function test.