Table 4

Characteristics of mucosal bleeding episodes by bleeding site

MenorrhagiaEpistaxisOral cavity
Number of bleeding episodes 32 42 26 
Total number of infusions administered 37 43 33 
Median (range) number of infusions per bleed 1 (1-2) 1 (1-2) 1 (1-4) 
Median VWF:RCo dose (IU/kg) 43.3 (39.9-95.1) 40.4 (23.8-90.2) 50.2 (23.8-184.9) 
Median (range) rFVIII dose (IU/kg) 30.6 (28.1-61.3) 28.7 (16.6-49.3) 36.9 (16.6-51.9) 
% bleeds (N = 100) rated* excellent or good (n excellent/good) 100% (31/1) 100% (41/1) 100% (26/0) 
MenorrhagiaEpistaxisOral cavity
Number of bleeding episodes 32 42 26 
Total number of infusions administered 37 43 33 
Median (range) number of infusions per bleed 1 (1-2) 1 (1-2) 1 (1-4) 
Median VWF:RCo dose (IU/kg) 43.3 (39.9-95.1) 40.4 (23.8-90.2) 50.2 (23.8-184.9) 
Median (range) rFVIII dose (IU/kg) 30.6 (28.1-61.3) 28.7 (16.6-49.3) 36.9 (16.6-51.9) 
% bleeds (N = 100) rated* excellent or good (n excellent/good) 100% (31/1) 100% (41/1) 100% (26/0) 
*

Rated according to a predefined 4-point scale (Table 1).

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