Patient characteristics
No. . | Sex/age, y . | BM involvement by biopsy or aspirate, % . | Disease status . | R-ISS . | Prior radiotherapy . | Previous therapy . | Dose of unlabeled Dara, mg . |
---|---|---|---|---|---|---|---|
1 | Male/59 | 25 | Newly diagnosed | Stage II | Yes | 0 | |
2 | Male/70 | 6 | Relapse by PET | Unknown | No | RVD, autologous stem cell transplantation; lenalidomide maintenance | 0 |
3 | Male/69 | 1 | Relapse in pleural lesion by PET | Stage III | Yes | RVD; pomalidomide, daratumumab, dexamethasone; autologous stem cell transplantation | 0 |
4 | Male/62 | 6.4 | Relapse by minimal positive PET | Stage I | No | RVD | 10 |
5 | Female/52 | 2 | Relapse by PET: diffuse widespread lytic lesions | Stage II | No | RVD | 10 |
6 | Female/55 | 5 | Biochemical relapse | Stage I | No | RVD; autologous stem cell transplantation | 10 |
7 | Female/55 | 60 | Newly diagnosed | Stage I | No | 45 | |
8 | Female/64 | 60 | Newly diagnosed | Stage II | No | 45 | |
9 | Male/67 | 0 | Recurrent plasmacytoma | Unknown | Yes | 45 | |
10 | Female/61 | 40 | Newly diagnosed | Stage I | No | 95 | |
11 | Male/72 | 0 | Suspicion of relapse as detected by MRI | Stage III | No | RVD; autologous stem cell transplantation; carfilzomib, lenalidomide, dexamethasone; daratumumab, lenalidomide | 95 |
12 | Female/78 | 40 | Newly diagnosed | No | 95 |
No. . | Sex/age, y . | BM involvement by biopsy or aspirate, % . | Disease status . | R-ISS . | Prior radiotherapy . | Previous therapy . | Dose of unlabeled Dara, mg . |
---|---|---|---|---|---|---|---|
1 | Male/59 | 25 | Newly diagnosed | Stage II | Yes | 0 | |
2 | Male/70 | 6 | Relapse by PET | Unknown | No | RVD, autologous stem cell transplantation; lenalidomide maintenance | 0 |
3 | Male/69 | 1 | Relapse in pleural lesion by PET | Stage III | Yes | RVD; pomalidomide, daratumumab, dexamethasone; autologous stem cell transplantation | 0 |
4 | Male/62 | 6.4 | Relapse by minimal positive PET | Stage I | No | RVD | 10 |
5 | Female/52 | 2 | Relapse by PET: diffuse widespread lytic lesions | Stage II | No | RVD | 10 |
6 | Female/55 | 5 | Biochemical relapse | Stage I | No | RVD; autologous stem cell transplantation | 10 |
7 | Female/55 | 60 | Newly diagnosed | Stage I | No | 45 | |
8 | Female/64 | 60 | Newly diagnosed | Stage II | No | 45 | |
9 | Male/67 | 0 | Recurrent plasmacytoma | Unknown | Yes | 45 | |
10 | Female/61 | 40 | Newly diagnosed | Stage I | No | 95 | |
11 | Male/72 | 0 | Suspicion of relapse as detected by MRI | Stage III | No | RVD; autologous stem cell transplantation; carfilzomib, lenalidomide, dexamethasone; daratumumab, lenalidomide | 95 |
12 | Female/78 | 40 | Newly diagnosed | No | 95 |
MRI, magnetic resonance imaging; RVD, lenalidomide/bortezomib/dexamethasone.