Characteristics of patients with BUC
| . | All patients (n = 422) . | Blood group O (n = 199) . | Blood group non-O (n = 223) . | P . |
|---|---|---|---|---|
| Age, mean (SD), y | 42.5 (15.7) | 43.5 (15.8) | 41.6 (15.5) | .223 |
| Female, n (%) | 363 (86.0) | 171 (85.9) | 192 (86.1) | .960 |
| Positive family history, n (%) | 153 (36.3) | 75 (37.7) | 78 (35.0) | .417 |
| White, n (%) | 417 (98.8) | 196 (98.5) | 221 (99.1) | .563 |
| Diabetes, n (%) | 5 (1.2) | 4 (2.0) | 1 (0.4) | .193 |
| Arterial hypertension, n (%) | 41 (9.7) | 20 (10.1) | 21 (9.4) | .870 |
| Hypothyroidism, n (%) | 10 (2.4) | 6 (3.0) | 4 (1.8) | .410 |
| Hemoglobin, mean (SD), g/dL | 13.6 (1.3) | 13.6 (1.2) | 13.5 (1.3) | .494 |
| Platelet count, mean (SD), ×109/L, | 252.9 (57.8) | 252.1 (55.0) | 253.5 (60.3) | .804 |
| APTT-STA, median (IQR), s | 35.5 (33.4-37.7) | 36.0 (34.0-38.6) | 34.8 (32.7-37.3) | <.001 |
| FVIII activity, median (IQR), % | 126 (103-162) | 110 (95-135) | 146 (119-181) | <.001 |
| VWF:Ag, median (IQR), U/mL | 99 (80-124.3) | 86 (73-103) | 110 (94-143) | <.001 |
| VWF:RCo, median (IQR), U/mL | 86 (69-126) | 72 (63-90) | 110 (78.25-140) | <.001 |
| . | All patients (n = 422) . | Blood group O (n = 199) . | Blood group non-O (n = 223) . | P . |
|---|---|---|---|---|
| Age, mean (SD), y | 42.5 (15.7) | 43.5 (15.8) | 41.6 (15.5) | .223 |
| Female, n (%) | 363 (86.0) | 171 (85.9) | 192 (86.1) | .960 |
| Positive family history, n (%) | 153 (36.3) | 75 (37.7) | 78 (35.0) | .417 |
| White, n (%) | 417 (98.8) | 196 (98.5) | 221 (99.1) | .563 |
| Diabetes, n (%) | 5 (1.2) | 4 (2.0) | 1 (0.4) | .193 |
| Arterial hypertension, n (%) | 41 (9.7) | 20 (10.1) | 21 (9.4) | .870 |
| Hypothyroidism, n (%) | 10 (2.4) | 6 (3.0) | 4 (1.8) | .410 |
| Hemoglobin, mean (SD), g/dL | 13.6 (1.3) | 13.6 (1.2) | 13.5 (1.3) | .494 |
| Platelet count, mean (SD), ×109/L, | 252.9 (57.8) | 252.1 (55.0) | 253.5 (60.3) | .804 |
| APTT-STA, median (IQR), s | 35.5 (33.4-37.7) | 36.0 (34.0-38.6) | 34.8 (32.7-37.3) | <.001 |
| FVIII activity, median (IQR), % | 126 (103-162) | 110 (95-135) | 146 (119-181) | <.001 |
| VWF:Ag, median (IQR), U/mL | 99 (80-124.3) | 86 (73-103) | 110 (94-143) | <.001 |
| VWF:RCo, median (IQR), U/mL | 86 (69-126) | 72 (63-90) | 110 (78.25-140) | <.001 |
APTT-STA, activated partial thromboplastin time, according to the STA coagulation analyzer.