Cox models of OS, DFS, TRM, and relapse for low/intermediate disease risk and low HCT-CI 0-2 subgroups
| TERS score . | HR . | 95% CI . | P . |
|---|---|---|---|
| Low/intermediate disease risk cohort | |||
| OS | |||
| 30-37.5 vs ≤29.5 | 1.99 | 1.32-2.99 | .001 |
| ≥38 vs ≤29.5 | 1.99 | 1.31-3.02 | .001 |
| DFS | |||
| 30-37.5 vs ≤29.5 | 1.54 | 1.07-2.22 | .020 |
| ≥38 vs ≤29.5 | 1.52 | 1.05-2.20 | .029 |
| TRM | |||
| 30-37.5 vs ≤29.5 | 2.26 | 1.24-4.10 | .008 |
| ≥38 vs ≤29.5 | 2.40 | 1.31-4.39 | .005 |
| Relapse | |||
| 30-37.5 vs ≤29.5 | 1.20 | 0.76-1.91 | .44 |
| ≥38 vs ≤29.5 | 1.13 | 0.70-1.82 | .61 |
| Low HCT-CI (0-2) cohort | |||
| OS | |||
| 30-37.5 vs ≤29.5 | 1.51 | 0.92-2.48 | .107 |
| ≥38 vs ≤29.5 | 1.29 | 0.74-2.26 | .364 |
| DFS | |||
| 30-37.5 vs ≤ 29.5 | 1.51 | 0.99-2.31 | .056 |
| ≥38 vs ≤29.5 | 1.28 | 0.81-2.04 | .294 |
| TRM | |||
| 30-37.5 vs ≤29.5 | 2.93 | 1.30-6.59 | .010 |
| ≥38 vs ≤29.5 | 2.67 | 1.14-6.26 | .024 |
| Relapse | |||
| 30-37.5 vs ≤29.5 | 0.98 | 0.58-1.67 | .952 |
| ≥38 vs ≤29.5 | 0.75 | 0.41-1.36 | .338 |
| TERS score . | HR . | 95% CI . | P . |
|---|---|---|---|
| Low/intermediate disease risk cohort | |||
| OS | |||
| 30-37.5 vs ≤29.5 | 1.99 | 1.32-2.99 | .001 |
| ≥38 vs ≤29.5 | 1.99 | 1.31-3.02 | .001 |
| DFS | |||
| 30-37.5 vs ≤29.5 | 1.54 | 1.07-2.22 | .020 |
| ≥38 vs ≤29.5 | 1.52 | 1.05-2.20 | .029 |
| TRM | |||
| 30-37.5 vs ≤29.5 | 2.26 | 1.24-4.10 | .008 |
| ≥38 vs ≤29.5 | 2.40 | 1.31-4.39 | .005 |
| Relapse | |||
| 30-37.5 vs ≤29.5 | 1.20 | 0.76-1.91 | .44 |
| ≥38 vs ≤29.5 | 1.13 | 0.70-1.82 | .61 |
| Low HCT-CI (0-2) cohort | |||
| OS | |||
| 30-37.5 vs ≤29.5 | 1.51 | 0.92-2.48 | .107 |
| ≥38 vs ≤29.5 | 1.29 | 0.74-2.26 | .364 |
| DFS | |||
| 30-37.5 vs ≤ 29.5 | 1.51 | 0.99-2.31 | .056 |
| ≥38 vs ≤29.5 | 1.28 | 0.81-2.04 | .294 |
| TRM | |||
| 30-37.5 vs ≤29.5 | 2.93 | 1.30-6.59 | .010 |
| ≥38 vs ≤29.5 | 2.67 | 1.14-6.26 | .024 |
| Relapse | |||
| 30-37.5 vs ≤29.5 | 0.98 | 0.58-1.67 | .952 |
| ≥38 vs ≤29.5 | 0.75 | 0.41-1.36 | .338 |
Effect: high- and intermediate-risk TERS score vs low-risk TERS score. TERS score was retained in all models. In low/intermediate risk cohort, age and donor type were included in Cox models for OS, DFS, and TRM; Cox model for OS also included year of transplantation; diagnosis was included in Cox model for relapse. In HCT-CI 0-2 cohort, Cox model for OS included age, diagnosis, donor type, and year of transplantation; Cox model for DFS included age and diagnosis; Cox model for TRM included age and donor type; Cox model for relapse included diagnosis and intensity.