Response to romidepsin as single agent or combinations in TFH vs non-TFH phenotype relapsed/refractory PTCL
| Response . | TFH (n = 76) . | Non-TFH (n = 51) . | . | ||
|---|---|---|---|---|---|
| ORR, n/total (%) . | CR, n/total (%) . | ORR, n/total (%) . | CR, n/total (%) . | P* . | |
| Overall (n = 127) | 43/76 (56.5) | 22/76 (28.9) | 15/51 (29.4) | 10/51 (19.6) | .0035 |
| Single agent (n = 97) | 32/59 (54.2) | 15/59 (25.4) | 12/38 (31.5) | 8/38 (21.0) | .0371 |
| Combinations (n = 30) | 11/18 (61.1) | 7/18 (38.8) | 3/12 (25.0) | 2/12 (16.6) | .0717 |
| Response . | TFH (n = 76) . | Non-TFH (n = 51) . | . | ||
|---|---|---|---|---|---|
| ORR, n/total (%) . | CR, n/total (%) . | ORR, n/total (%) . | CR, n/total (%) . | P* . | |
| Overall (n = 127) | 43/76 (56.5) | 22/76 (28.9) | 15/51 (29.4) | 10/51 (19.6) | .0035 |
| Single agent (n = 97) | 32/59 (54.2) | 15/59 (25.4) | 12/38 (31.5) | 8/38 (21.0) | .0371 |
| Combinations (n = 30) | 11/18 (61.1) | 7/18 (38.8) | 3/12 (25.0) | 2/12 (16.6) | .0717 |
P values have been calculated with the Fisher’s exact test.