Criteria for diagnosis of embolic stroke of undetermined source89
| Four diagnostic criteria . |
|---|
| 1. Nonlacunar ischemic stroke on CT or MRI |
| “Lacunar” defined as subcortical infarct ≤1.5 cm (≤2.0 cm on MRI diffusion images) in largest dimension, including on MRI diffusion-weighted images, and in distribution of small, penetrating cerebral arteries of cerebral hemispheres and pons; visualization by CT usually needs delayed imaging >24-28 h after stroke onset |
| 2. Absence of atherosclerosis (extra- or intracranial) causing ≥50% luminal stenosis in arteries supplying the ischemic area |
| 3. No major risk cardioembolic source |
| “Major risk” source includes atrial fibrillation (permanent or paroxysmal), sustained atrial flutter, intracardiac thrombus, prosthetic cardiac valve, cardiac tumors, mitral stenosis, recent (<4 wk) myocardial infarction, left ventricular ejection fraction <30%, valvular vegetations, or infective endocarditis |
| 4. No other specific cause of stroke identified |
| Other causes including arteritis, dissection, vasospasm, substance use |
| Four diagnostic criteria . |
|---|
| 1. Nonlacunar ischemic stroke on CT or MRI |
| “Lacunar” defined as subcortical infarct ≤1.5 cm (≤2.0 cm on MRI diffusion images) in largest dimension, including on MRI diffusion-weighted images, and in distribution of small, penetrating cerebral arteries of cerebral hemispheres and pons; visualization by CT usually needs delayed imaging >24-28 h after stroke onset |
| 2. Absence of atherosclerosis (extra- or intracranial) causing ≥50% luminal stenosis in arteries supplying the ischemic area |
| 3. No major risk cardioembolic source |
| “Major risk” source includes atrial fibrillation (permanent or paroxysmal), sustained atrial flutter, intracardiac thrombus, prosthetic cardiac valve, cardiac tumors, mitral stenosis, recent (<4 wk) myocardial infarction, left ventricular ejection fraction <30%, valvular vegetations, or infective endocarditis |
| 4. No other specific cause of stroke identified |
| Other causes including arteritis, dissection, vasospasm, substance use |