Table 1.

Demographic characteristics of first-time donors and proportions HIV-positive in pre- and postimplementation periods

GroupPreimplementation periodPostimplementation period
Donations N (% of total)HIV+ NHIV+ /105 (95% CI)*Donations N (% of total)HIV+ NHIV+ /105 (95% CI)*
Sex       
 Male 867 223 (48.1) 105 12.11 (9.90-14.66) 1 415 738 (47.4) 212 14.98 (13.03-17.13) 
 Female 937 534 (51.9) 25 2.67 (1.73-3.94) 1 569 234 (52.6) 49 3.12 (2.31-4.13) 
Age group, y       
 16-17 449 204 (24.9) 10 2.23 (1.07-4.09) 641 387 (21.5) 31 4.83 (3.28-6.86) 
 18-24 388 828 (21.5) 31 7.97 (5.42-11.32) 580 174 (19.4) 57 9.83 (7.44-12.73) 
 25-39 424 687 (23.5) 56 13.19 (9.96-17.12) 757 303 (25.4) 94 12.41 (10.03-15.19) 
 40-54 308 752 (17.1) 30 9.72 (6.56-13.87) 551 729 (18.5) 60 10.88 (8.30-14.00) 
 55+ 233 303 (12.9) 1.29 (0.27-3.76) 454 417 (15.2) 19 4.18 (2.52-6.53) 
Race/ethnicity       
 White 1 190 489 (66.0) 36 3.02 (2.12-4.19) 2 069 287 (69.3) 82 3.96 (3.15-4.92) 
 Black or African American 127 762 (7.1) 65 50.88 (39.27-64.84) 211 055 (7.1) 109 51.65 (42.41-62.30) 
 Asian 66 745 (3.7) 1.50 (0.04-8.35) 125 360 (4.2) 3.19 (0.87-8.17) 
 Hispanic/Latino ethnicity 249 256 (13.8) 20 8.02 (4.90-12.39) 434 662 (14.6) 51 11.73 (8.74-15.43) 
 Other race/ethnicity 170 522 (9.4) 4.69 (2.03-9.24) 144 646 (4.8) 15 10.37 (5.80-17.10) 
Geographic region§       
 Midwest 394 636 (21.9) 11 2.79 (1.39-4.99) 615 126 (20.6) 26 4.23 (2.76-6.19) 
 Northeast 334 941 (18.6) 12 3.58 (1.85-6.26) 526 052 (17.6) 21 3.99 (2.47-6.10) 
 South 673 702 (37.3) 92 13.66 (11.01-16.75) 1 098 826 (36.8) 169 15.38 (13.15-17.88) 
 West 400 414 (22.2) 15 3.75 (2.10-6.18) 743 374 (24.9) 45 6.05 (4.42-8.10) 
Total 1 804 774 (100.0) 130 7.20 (6.02-8.55) 2 985 010 (100.0) 261 8.74 (7.72-9.87) 
GroupPreimplementation periodPostimplementation period
Donations N (% of total)HIV+ NHIV+ /105 (95% CI)*Donations N (% of total)HIV+ NHIV+ /105 (95% CI)*
Sex       
 Male 867 223 (48.1) 105 12.11 (9.90-14.66) 1 415 738 (47.4) 212 14.98 (13.03-17.13) 
 Female 937 534 (51.9) 25 2.67 (1.73-3.94) 1 569 234 (52.6) 49 3.12 (2.31-4.13) 
Age group, y       
 16-17 449 204 (24.9) 10 2.23 (1.07-4.09) 641 387 (21.5) 31 4.83 (3.28-6.86) 
 18-24 388 828 (21.5) 31 7.97 (5.42-11.32) 580 174 (19.4) 57 9.83 (7.44-12.73) 
 25-39 424 687 (23.5) 56 13.19 (9.96-17.12) 757 303 (25.4) 94 12.41 (10.03-15.19) 
 40-54 308 752 (17.1) 30 9.72 (6.56-13.87) 551 729 (18.5) 60 10.88 (8.30-14.00) 
 55+ 233 303 (12.9) 1.29 (0.27-3.76) 454 417 (15.2) 19 4.18 (2.52-6.53) 
Race/ethnicity       
 White 1 190 489 (66.0) 36 3.02 (2.12-4.19) 2 069 287 (69.3) 82 3.96 (3.15-4.92) 
 Black or African American 127 762 (7.1) 65 50.88 (39.27-64.84) 211 055 (7.1) 109 51.65 (42.41-62.30) 
 Asian 66 745 (3.7) 1.50 (0.04-8.35) 125 360 (4.2) 3.19 (0.87-8.17) 
 Hispanic/Latino ethnicity 249 256 (13.8) 20 8.02 (4.90-12.39) 434 662 (14.6) 51 11.73 (8.74-15.43) 
 Other race/ethnicity 170 522 (9.4) 4.69 (2.03-9.24) 144 646 (4.8) 15 10.37 (5.80-17.10) 
Geographic region§       
 Midwest 394 636 (21.9) 11 2.79 (1.39-4.99) 615 126 (20.6) 26 4.23 (2.76-6.19) 
 Northeast 334 941 (18.6) 12 3.58 (1.85-6.26) 526 052 (17.6) 21 3.99 (2.47-6.10) 
 South 673 702 (37.3) 92 13.66 (11.01-16.75) 1 098 826 (36.8) 169 15.38 (13.15-17.88) 
 West 400 414 (22.2) 15 3.75 (2.10-6.18) 743 374 (24.9) 45 6.05 (4.42-8.10) 
Total 1 804 774 (100.0) 130 7.20 (6.02-8.55) 2 985 010 (100.0) 261 8.74 (7.72-9.87) 

Only allogeneic first-time donations with valid HIV results and known donation procedure included.

*

Confidence intervals were calculated using the Clopper-Pearson exact method, which is conservative.

In the preimplementation period, 17 first-time donations lacked sex information, and in the postimplementation period, 38 donations lacked sex information.

Combined category consisting of American Indian or Alaska Native, more than one race, other race, and unknown race/ethnicity. In the preimplementation period, 6.3% of first-time donations had missing race/ethnicity and in the postimplementation period, 1.5% of first-time donations had missing race/ethnicity.

§

First-time donations from donors residing outside the continental United States (304 in the preimplementation period and 598 in the postimplementation period) and with missing residence information (777 in the preimplementation period and 1034 in the postimplementation period) were excluded.

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