Table 1. Subject characteristics . SCD... | American Society of Hematology

Table 1.

Subject characteristics

	SCD group	Control group	P
	n = 17	n = 16	P
Diagnosis, n (%)
SCD-SS	14 (82)	—
SCD-S β⁰ Thal	2 (12)	—
SCD-S β⁺ Thal	1 (6)	—
Sickle cell trait	—	5 (31)
HbAA	—	11 (69)
Mean age, y (SD)	21.6 (6.9)	22 (8.1)	.89*
Sex, n (%)			.62†
Male	11 (65)	9 (56)
Female	6 (35)	7 (44)
Race/ethnicity, n (%)			.94†
African American	15 (88)	14 (88)
Hispanic	2 (12)	2 (12)
Mean Hb, g/dL, (SD)	9.1 (1.5)	13.1 (1.2)	<.0001*
STAI anxiety score, median (IQR)
Y1 (now)	23 (20-31.5)	25 (22.2-30.2)	.5‡
Y2 (in general)	28 (24-36.5)	29 (25-35.2)	.9‡
PASS, median (IQR)	50 (29.5-59.5)	19.5 (9.5-37.5)	.013‡
Median threshold temperature, °C (IQR)
Cold detection	22 (15.7-27.2)	21.3 (18.1-24.5)	.74‡
Heat detection	39.6 (36.8-43.9)	40.7 (37.3-43.8)	.81‡
Heat pain	49.1 (46.7- 50)	48.7 (45.3-50)	.64‡
Cold pain	5.6 (0.3-11.8)	7.5 (1.5-14.7)	.48‡

	SCD group	Control group	P
	n = 17	n = 16	P
Diagnosis, n (%)
SCD-SS	14 (82)	—
SCD-S β⁰ Thal	2 (12)	—
SCD-S β⁺ Thal	1 (6)	—
Sickle cell trait	—	5 (31)
HbAA	—	11 (69)
Mean age, y (SD)	21.6 (6.9)	22 (8.1)	.89*
Sex, n (%)			.62†
Male	11 (65)	9 (56)
Female	6 (35)	7 (44)
Race/ethnicity, n (%)			.94†
African American	15 (88)	14 (88)
Hispanic	2 (12)	2 (12)
Mean Hb, g/dL, (SD)	9.1 (1.5)	13.1 (1.2)	<.0001*
STAI anxiety score, median (IQR)
Y1 (now)	23 (20-31.5)	25 (22.2-30.2)	.5‡
Y2 (in general)	28 (24-36.5)	29 (25-35.2)	.9‡
PASS, median (IQR)	50 (29.5-59.5)	19.5 (9.5-37.5)	.013‡
Median threshold temperature, °C (IQR)
Cold detection	22 (15.7-27.2)	21.3 (18.1-24.5)	.74‡
Heat detection	39.6 (36.8-43.9)	40.7 (37.3-43.8)	.81‡
Heat pain	49.1 (46.7- 50)	48.7 (45.3-50)	.64‡
Cold pain	5.6 (0.3-11.8)	7.5 (1.5-14.7)	.48‡

Significant P-values are in bold.

Student t test.

χ² test.

Wilcoxon rank sum test.