Table 1. 13q12.2 deletions in 27 cases... | American Society of Hematology

Table 1.

13q12.2 deletions in 27 cases of ALL

Case	Deleted region*	Size, bp	FLT3 mutation	Deletion at diagnosis	Deletion at relapse
1	chr13:28 689 519-28 818 033†	128 514	p.A680V	Yes	Yes
2	chr13:28 686 699-28 818 553†	131 854	No	Yes	Yes
3	chr13:28 691 097-28 795 606	104 509	p.D835Y	Yes	N/A
4	chr13:28 675 905-28 816 917†	141 012	p.I867S	Yes	N/A
5	chr13:28 678 803-28 814 370	135 567	No	Yes	N/A
6	chr13:28 689 487-28 818 033†	128 546	No	Yes	N/A
7	chr13:28 675844-28 779 095†	103 251	ITD	Yes	N/A
8	chr13:28 678 544-28 717 233†	38 689	No	Yes	N/A
9	chr13:28 672 989-28 816 869†	143 880	No	Yes	N/A
10	chr13:28 681 356-28 816 438	135 082	NK	Yes	N/A
11	chr13:28 681 356-28 816 438	135 082	NK	Yes	N/A
12	chr13:28 675 878-28 817 064†	141 186	No	Yes	N/A
13	chr13:28 682 922-28 798 410†	115 488	No	Yes	No
14	chr13:28 706 767-28 749 112†	42 345	No	No	Yes
15	chr13:28 675 750-28 835 054†	159 304	p.M837P	Yes	Yes
16	chr13:28 685 061-28 813 774	128 713	No	Yes	N/A
17	chr13:28 689 100-28 801 000	111 900	p.R834dup	Yes	N/A
18	chr13:28 689 223-28 722 472	33 249	No	Yes	N/A
19	chr13:28 690 533-28 829 444	138 911	No	Yes	N/A
20	chr13:28 691 097-28 828 603	137 506	No	Yes	N/A
21	chr13:28 719 402-28 814 420	95 018	No	Yes	N/A
22	chr13:28 687 654-28 759 548	71 894	ITD	Yes	N/A
23	chr13:28 712 891-28 813 915	101 024	No	Yes	N/A
24	chr13:28 712 891-28 813 915	101 024	No	Yes	N/A
25	chr13:28 712 685-28 830 678	117 993	No	Yes	N/A
26	chr13:28 712 435-28 752 128	39 693	p.S838_D839insEG/p.N841T	Yes	N/A
27	chr13:28 712 685-28 813 851	101 166	p.L576P	Yes	N/A

Case	Deleted region*	Size, bp	FLT3 mutation	Deletion at diagnosis	Deletion at relapse
1	chr13:28 689 519-28 818 033†	128 514	p.A680V	Yes	Yes
2	chr13:28 686 699-28 818 553†	131 854	No	Yes	Yes
3	chr13:28 691 097-28 795 606	104 509	p.D835Y	Yes	N/A
4	chr13:28 675 905-28 816 917†	141 012	p.I867S	Yes	N/A
5	chr13:28 678 803-28 814 370	135 567	No	Yes	N/A
6	chr13:28 689 487-28 818 033†	128 546	No	Yes	N/A
7	chr13:28 675844-28 779 095†	103 251	ITD	Yes	N/A
8	chr13:28 678 544-28 717 233†	38 689	No	Yes	N/A
9	chr13:28 672 989-28 816 869†	143 880	No	Yes	N/A
10	chr13:28 681 356-28 816 438	135 082	NK	Yes	N/A
11	chr13:28 681 356-28 816 438	135 082	NK	Yes	N/A
12	chr13:28 675 878-28 817 064†	141 186	No	Yes	N/A
13	chr13:28 682 922-28 798 410†	115 488	No	Yes	No
14	chr13:28 706 767-28 749 112†	42 345	No	No	Yes
15	chr13:28 675 750-28 835 054†	159 304	p.M837P	Yes	Yes
16	chr13:28 685 061-28 813 774	128 713	No	Yes	N/A
17	chr13:28 689 100-28 801 000	111 900	p.R834dup	Yes	N/A
18	chr13:28 689 223-28 722 472	33 249	No	Yes	N/A
19	chr13:28 690 533-28 829 444	138 911	No	Yes	N/A
20	chr13:28 691 097-28 828 603	137 506	No	Yes	N/A
21	chr13:28 719 402-28 814 420	95 018	No	Yes	N/A
22	chr13:28 687 654-28 759 548	71 894	ITD	Yes	N/A
23	chr13:28 712 891-28 813 915	101 024	No	Yes	N/A
24	chr13:28 712 891-28 813 915	101 024	No	Yes	N/A
25	chr13:28 712 685-28 830 678	117 993	No	Yes	N/A
26	chr13:28 712 435-28 752 128	39 693	p.S838_D839insEG/p.N841T	Yes	N/A
27	chr13:28 712 685-28 813 851	101 166	p.L576P	Yes	N/A

bp, base pair; N/A, data not available (no relapse or no sample available); NK, not known.

Minimally deleted region based on SNP array analysis or WES copy number data unless otherwise indicated.

Breakpoint validated by WGS.