Multivariable model of factors associated with survival
| Factor . | Progression-free survival . | Overall survival . | ||||
|---|---|---|---|---|---|---|
| P for uni . | HR [95% CI] . | P for multi . | P for uni . | HR [95% CI] . | P for multi . | |
| Stage III-IV | .04 | 0.8 [0.3-2.2] | .69 | — | — | — |
| IPI 3-4 | .002 | 0.8 [0.4-1.6] | .76 | .001 | 0.6 [0.3-1.4] | .03 |
| LDH > ULN | <.001 | 0.3 [0.1-0.7] | .007 | <.001 | 0.1 [0.03-0.7] | .01 |
| Grade ≥ 3 ICANS | .02 | 0.7 [0.4-1.3] | .29 | .001 | 0.5 [0.2-0.9] | .02 |
| Factor . | Progression-free survival . | Overall survival . | ||||
|---|---|---|---|---|---|---|
| P for uni . | HR [95% CI] . | P for multi . | P for uni . | HR [95% CI] . | P for multi . | |
| Stage III-IV | .04 | 0.8 [0.3-2.2] | .69 | — | — | — |
| IPI 3-4 | .002 | 0.8 [0.4-1.6] | .76 | .001 | 0.6 [0.3-1.4] | .03 |
| LDH > ULN | <.001 | 0.3 [0.1-0.7] | .007 | <.001 | 0.1 [0.03-0.7] | .01 |
| Grade ≥ 3 ICANS | .02 | 0.7 [0.4-1.3] | .29 | .001 | 0.5 [0.2-0.9] | .02 |
Only factors significantly associated in univariable analysis were included in the model. Bold numbers indicate significant P values.
CI, confidence internal; HR, hazard ratio; multi, multivariable; uni, univariable.