Detection of BMI
| . | Detection of BMI by PET/CT alone using BMB as reference standard* . | Detection of BMI when using combined BMB and PET/CT as reference standard . | ||||
|---|---|---|---|---|---|---|
| Absolute nos.† . | Percentage (95% CI) . | PET/CT† . | Percentage (95% CI) . | BMB† . | Percentage (95% CI) . | |
| Sensitivity | 46/81 | 57 (45-68) | 78/(78 + 35) | 69 (60-77) | 81/(81 + 32) | 72 (62-80) |
| Specificity | 148/180 | 82 (76-84) | N/A‡ | N/A‡ | N/A‡ | N/A‡ |
| PPV | 46/(46 + 32) | 59 (47-70) | N/A‡ | N/A‡ | N/A‡ | N/A‡ |
| NPV | 148/183 | 81 (74-86) | 148/183 | 81 (74-86) | 148/(148 + 32) | 82 (76-88) |
| Accuracy | (46 + 148)/261 | 74 (69-80) | (46 + 148 + 32)/261 | 87 (82-90) | (46 + 148 + 35)/261 | 88 (83-91) |
| . | Detection of BMI by PET/CT alone using BMB as reference standard* . | Detection of BMI when using combined BMB and PET/CT as reference standard . | ||||
|---|---|---|---|---|---|---|
| Absolute nos.† . | Percentage (95% CI) . | PET/CT† . | Percentage (95% CI) . | BMB† . | Percentage (95% CI) . | |
| Sensitivity | 46/81 | 57 (45-68) | 78/(78 + 35) | 69 (60-77) | 81/(81 + 32) | 72 (62-80) |
| Specificity | 148/180 | 82 (76-84) | N/A‡ | N/A‡ | N/A‡ | N/A‡ |
| PPV | 46/(46 + 32) | 59 (47-70) | N/A‡ | N/A‡ | N/A‡ | N/A‡ |
| NPV | 148/183 | 81 (74-86) | 148/183 | 81 (74-86) | 148/(148 + 32) | 82 (76-88) |
| Accuracy | (46 + 148)/261 | 74 (69-80) | (46 + 148 + 32)/261 | 87 (82-90) | (46 + 148 + 35)/261 | 88 (83-91) |
N/A, not applicable.
Note that this represents an unrealistic worst-case scenario, assuming that all focal FDG uptake outside of the location of BMB was false-positive. These data are only reported for completeness.
Values represent absolute numbers, and values in parentheses represent the sum of absolute numbers shown in Table 3 used for calculations as per standard formulas for sensitivity, specificity, PPV, NPV, and accuracy.
Missing reference for the false-positives.